Who is This Test For?
The FLUIDS iQ test for intestinal permeability (“Leaky Gut”), measuring levels of Zonulin and its related family of peptides (Zonulin FP), is the cornerstone of our Intestinal iQ™ series of wellness tests. We’re proud to have been the first to develop and introduce this specific test to North America
Zonulin is a protein that modulates the permeability of tight junctions between cells of the digestive tract wall. Zonulin, and its family of peptides, are found within intestinal cells and, interestingly, its production and release mimic the effect of certain bacterial toxins. Once triggered, Zonulin plays an important role in the creation of what we think of as gut “leakiness.”
The takeaway? The gliadin-Zonulin “leak” effect occurs not just in people with celiac disease or gluten-sensitivity. It occurs in everyone, but the effect is longer and more pronounced in the intestinal cells of people with celiac disease.